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Hormone Replacement Therapy (HRT) and Osteoporosis: Prevention and Treatment
Hormone decline is a primary cause of osteoporosis. This article explains how hormone replacement therapy (HRT) restores estrogen and testosterone balance to prevent bone loss, improve bone density, and reduce fracture risk. Learn when HRT is appropriate and how it compares to traditional osteoporosis treatments.

David Stephen Klein, MD FACA FACPM
6 days ago3 min read


Visceral Adiposity: Why Belly Fat Is A Metabolic And Longevity Risk
Visceral fat is not merely stored energy—it is a biologically active tissue that drives insulin resistance, cardiovascular disease, cognitive decline, and accelerated aging. Many individuals with normal weight harbor excess visceral fat. Identifying and reducing it early can dramatically improve metabolic health and long-term healthspan.

David S. Klein, MD FACA FACPM
Mar 103 min read


Fatty Liver Disease (MASLD): The Metabolic Warning Sign of Insulin Resistance
Metabolic dysfunction–associated steatotic liver disease (MASLD), formerly called fatty liver, is not a liver problem alone—it is a systemic marker of insulin resistance. Often silent for years, MASLD signals elevated cardiometabolic, cognitive, and longevity risk long before abnormal liver enzymes or diabetes appear.

David S. Klein, MD FACA FACPM
Feb 173 min read


Insulin Resistance: The Hidden Precursor to Cardiovascular Disease, Dementia, and Accelerated Aging
Insulin resistance often develops years before diabetes, heart disease, or dementia are diagnosed. During this silent phase, metabolic dysfunction damages blood vessels, the brain, and cellular aging pathways. Understanding insulin resistance early allows for targeted intervention that can meaningfully reduce cardiovascular risk, cognitive decline, and accelerated biological aging.

David S. Klein, MD FACA FACPM
Feb 93 min read


The Link Between Fructose Beverages and Non-Alcoholic Fatty Liver Disease
Understanding the connection between fructose-containing beverages and fatty liver disease empowers people to make informed choices. By reducing sugary drink intake and adopting healthier habits, it is possible to protect the liver and improve overall health.

David S. Klein, MD FACA FACPM
Nov 10, 20255 min read
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