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Peptide therapy: promise, pitfalls and what patients should know
Peptides are short amino-acid chains that act as highly specific signaling molecules and have become a major class of modern therapeutics. More than 80 peptide drugs are approved worldwide, including insulin, incretin analogues such as GLP-1 receptor agonists, vasopressin analogues and linaclotide. These agents provide effective, targeted therapy in endocrine, metabolic, gastrointestinal and oncologic indications, supported by robust randomized clinical trials and rigorous ma

David S. Klein, MD FACA FACPM
Dec 5, 20258 min read


Have a Happy Holiday: Detox Essentials
Detoxification is often misunderstood as a fad, yet it remains a central physiological process essential for human survival. The holiday season—marked by stress, alcohol consumption, disrupted sleep, and poor dietary choices—places a substantial metabolic burden on the liver, gallbladder, kidneys, lungs, and intestinal tract. This blog outlines the science behind the body’s three-phase detox pathway and explains how targeted nutritional support can enhance natural clearance m

David S. Klein, MD FACA FACPM
Dec 2, 202510 min read


Zepbound® (tirzepatide) and Menopausal Weight Loss: A Promising Ally for a Challenging Transition
Menopause is a time of profound metabolic transition, and for many women, weight gain becomes an unwelcome companion despite disciplined efforts with diet and exercise. As estrogen levels fall, resting metabolism slows, visceral fat accumulates, and insulin sensitivity declines—creating a perfect storm that resists traditional weight-loss approaches. Zepbound® (tirzepatide) offers a meaningful breakthrough for women facing these challenges. By activating both GIP and GLP-1 re

David S. Klein, MD FACA FACPM
Nov 25, 20253 min read


Bioidentical Hormone Replacement Therapy (BHRT): What it is, who benefits, and what the FDA says now
Bioidentical Hormone Therapy in Central Florida | Stages of Life Medical Institute

David S. Klein, MD FACA FACPM
Nov 12, 20254 min read


The Link Between Fructose Beverages and Non-Alcoholic Fatty Liver Disease
Understanding the connection between fructose-containing beverages and fatty liver disease empowers people to make informed choices. By reducing sugary drink intake and adopting healthier habits, it is possible to protect the liver and improve overall health.

David S. Klein, MD FACA FACPM
Nov 10, 20255 min read


Uncovering the Science: How Berberine Unleashes Its Healing Potential: Diabetes Control, Cancer Prevention and Weight Loss
Berberine, a natural compound from several plants, is gaining much attention in health circles for its impressive medicinal properties. This bright yellow alkaloid, used for centuries in ancient Chinese and Ayurvedic medicine, is now the focus of modern research. It may play a significant role in enhancing metabolic health and supporting cardiovascular wellness, offering a profound perspective on holistic health.

David S. Klein, MD FACA FACPM
Oct 21, 20255 min read


Zepbound (Tirzepatide) for Weight Loss and Obstructive Sleep Apnea: Approved by Many Medicare Prescription Plans
Zepbound is a different type of GLP-1 used to treat weight problems. It is an advancement over the Wegovy-Ozempic class in that it is a dual receptor acting agent.
More so, it is covered under many Medicare Prescription plans in patients that suffer from sleep apnea (obstructive sleep apnea) after documentation with sleep study.

David S. Klein, MD FACA FACPM
Oct 17, 20254 min read


IT IS NOW AVAILABLE!!!!! New Zealand Hops Flower Extract? A Natural GLP-1 Agonist for Weight Loss. An Orally Available Alternative to Wegovy, Ozempic and Zepbound
Calocurb is a high quality New Zealand Hops Flower Extract, containing high potency nutraceuticals that inhibit appetite.
This is most remarkable after you finish your prescription GLP-1 medicine, and minimizes the rebound hunger that very often follows discontinuation of the GLP-1 agens.
It can be used concurrently with the injectables, and this may minimize the physiological down regulation of GLP-1 receptors, and may reduce the dosage of the prescription item leading to

David S. Klein, MD FACA FACPM
Sep 29, 20254 min read


GLP-1 Medications and Dementia Prevention. Weight Loss, Diabetes Risk Reduction and Alzheimer's Prevention, as a Bonus!
Popular GLP-1 medications, like Ozempic and Zepbound may provide prevention of Alzheimer's Dementia on top of the weight reduction and diabetes control.
Reduction of weight helps with Sleep Apnea, as well. Understand the need for medical monitoring if you are going to use these medications.
This is a worthy read to give a comprehensive presentation as to the risks/benefits as well as the need for vigilance.

David S. Klein, MD FACA FACPM
Sep 23, 202512 min read


Fructose is the Silent Killer in the North American Diet. Inflammation, Early Death, Kidney Failure, Arthritis.
Fructose in your diet is silently killing us. I will give you a simplified overview of an enormous problem with a simple solution.

David S. Klein, MD FACA FACPM
Apr 7, 20254 min read
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