top of page

Search


Environmental Heat, Alcohol, and Hyponatremia. Deadly in Summer
Hot weather can create more than dehydration. Sweating causes water and sodium loss, while heat-related vasodilation can lower blood pressure. Add alcohol, medications, poor food intake, or excessive plain water and the result may be orthostatic dizziness, hyponatremia, instability, and falls. Learn why older adults are especially vulnerable, which medications increase risk, when electrolyte replacement may matter, and which symptoms require urgent medical evaluation.

David Stephen Klein, MD FACA FACPM
2 days ago14 min read


Pulse Pressure, Aging, and Stroke Risk: Why the “Ideal” Number Changes With Age
Pulse pressure is the difference between systolic and diastolic blood pressure. For example, 120/80 mmHg produces a pulse pressure of 40 mmHg. Pulse pressure often widens with age as large arteries become stiffer. In older adults, a persistently wide pulse pressure may indicate increased arterial stiffness and cardiovascular risk, including stroke risk. It should be interpreted together with age, systolic and diastolic pressures, medical conditions, and overall cardiovascular

David Stephen Klein, MD FACA FACPM
Aug 149 min read


C15:0 (Pentadecanoic Acid): Could This Be the First Newly Recognized Essential Fatty Acid in Nearly 100 Years?
Could C15:0 (pentadecanoic acid) become the first newly recognized essential fatty acid in nearly a century? Emerging research suggests this naturally occurring odd-chain saturated fatty acid may support healthy cell membranes, mitochondrial function, metabolic health, and healthy aging. Learn what current science tells us about food sources, supplements, recommended intake, and why researchers are paying close attention to this unique nutrient.

David Stephen Klein, MD FACA FACPM
Aug 77 min read


Low-Dose Lithium for Mild to Moderate Depression: Can a Time-Tested Mineral Improve Mood, Protect the Brain, and Promote Healthy Aging?
Could a medication long used for bipolar disorder also help support mood, protect the brain, and promote healthy aging at much lower doses? Emerging research suggests low-dose lithium may enhance neuroplasticity, reduce neuroinflammation, improve mitochondrial function, and influence pathways involved in depression and cognitive decline. Learn the current science, safety considerations, and how a systems-based evaluation may improve outcomes.

David Stephen Klein, MD FACA FACPM
Jul 2812 min read


Quercetin for Diabetes and Insulin Resistance: Could Nature's SGLT-2 Inhibitor Support Better Metabolic Health?
Quercetin is a plant compound found in onions, apples, berries, and capers. Emerging research suggests that certain forms may influence glucose absorption and some of the transport pathways associated with SGLT activity. Could this help support diabetes, insulin resistance, weight management, and metabolic health? Learn what is established, what remains theoretical, and why quercetin should complement—not replace—appropriate medical treatment.

David Stephen Klein, MD FACA FACPM
Jul 2413 min read


Adrenal Dysfunction and Adrenal Fatigue: Vital to Life, Yet Often Overlooked in Modern Medicine
The adrenal glands are among the body’s most vital yet overlooked organs, controlling stress adaptation, inflammation, blood pressure, metabolism, immune balance, and energy production. While severe adrenal failure such as Addison’s Disease is recognized in medicine, milder adrenal dysfunction often goes undiagnosed for years. Chronic stress, poor sleep, illness, medications, and nutritional deficiencies can impair adrenal function long before traditional testing reveals dise

David Stephen Klein, MD FACA FACPM
Jul 215 min read


Lactoferrin-Rich Colostrum and Better Sleep
Quality sleep depends on far more than melatonin. Emerging research suggests that lactoferrin-rich bovine colostrum may promote restorative sleep by reducing inflammation, supporting the gut-brain axis, balancing immune function, and maintaining healthy iron metabolism. Rather than acting as a sedative, lactoferrin helps restore the biologic environment necessary for healthier sleep—and potentially healthier aging.

David Stephen Klein, MD FACA FACPM
Jul 2011 min read


DHA and Dry Eye Disease: The Missing Nutrient in Ocular Surface Health
Dry eye disease is often treated with artificial tears, but emerging research suggests the problem may run much deeper. Deficiency of DHA, a critical omega-3 fatty acid concentrated in the retina and ocular surface, may contribute to inflammation, tear instability, and meibomian gland dysfunction. Understanding the nutritional connection between DHA and ocular health may provide a more effective long-term strategy for improving comfort, protecting vision, and reducing chronic

David Stephen Klein, MD FACA FACPM
Jul 146 min read


Can a Simple CBC Predict Future Dementia Risk?
The Monocyte-to-Lymphocyte Ratio and Its Emerging Role in Cognitive Decline. One of the cheapest test that is currently available. Can a Simple CBC Predict Future Dementia Risk? Understanding how the Monocyte-to-Lymphocyte Ratio (MLR) may reveal early inflammatory changes associated with Alzheimer’s disease, vascular dementia, and accelerated cognitive aging. Quick Look Could a routine complete blood count reveal early warning signs of future dementia? A growing body of evide

David Stephen Klein, MD FACA FACPM
Jul 75 min read


Pre-Diabetes: Insulin Resistance, Is It a Real Condition — Or a Warning Sign We Ignore at Our Own Risk?
Many people are told they have pre-diabetes and assume it simply means they may someday develop diabetes.
The truth is far more concerning.
Long before someone officially develops Type 2 diabetes, elevated insulin levels and subtle abnormalities in blood sugar regulation may already be damaging blood vessels, nerves, kidneys, and even the brain.
Prediabetes is not almost disease.
It is often the earliest measurable sign that metabolic dysfunction has already begun.
The g

David Stephen Klein, MD FACA FACPM
Jul 36 min read
bottom of page
