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Trigeminal Neuralgia: Understanding the Most Severe Facial Pain—and Emerging Targeted Treatment Options
Trigeminal neuralgia is one of the most severe pain conditions encountered in medicine. This physician-guided review explains the anatomy of the trigeminal nerve, why pain occurs, and how modern therapies—including targeted topical anticonvulsants and anti-inflammatory agents—can provide relief. Learn how nerve-specific diagnosis improves outcomes and expands treatment beyond traditional medications and surgery.

David Stephen Klein, MD FACA FACPM
Apr 16 min read


Journavx™ (Suzetrigine): A New Direction in Pain Management Without Opioids
Journavx (suzetrigine) is a novel non-opioid pain medication that targets Nav1.8 sodium channels in peripheral nerves. It offers effective pain relief without sedation or addiction risk, representing a new direction in modern pain management.

David Stephen Klein, MD FACA FACPM
Mar 303 min read


Alpha Lipoic Acid and Healthy Aging
Alpha lipoic acid supports mitochondrial energy production, improves insulin sensitivity, and protects vascular and nerve health. This physician-to-patient guide explains how ALA may support disease prevention and healthy aging when used within a comprehensive longevity strategy.

David Stephen Klein, MD FACA FACPM
Mar 274 min read


Nutrition and Pain Management: What Foods Make Pain Worse?
Many patients with chronic pain notice that certain foods make their symptoms worse. Refined sugar, ultra-processed foods, industrial seed oils, and alcohol can increase inflammation and amplify pain signals in the body. Understanding how nutrition influences inflammatory pathways allows patients to make dietary changes that may reduce pain and improve overall health.

David Stephen Klein, MD FACA FACPM
Mar 184 min read


Bromelain: A Natural Anti-Inflammatory Enzyme with Cardiovascular Benefits
Bromelain is a powerful proteolytic enzyme derived from pineapple that can reduce inflammation, improve circulation, and inhibit excessive platelet aggregation. When taken on an empty stomach, bromelain is absorbed systemically rather than used for digestion, allowing it to support cardiovascular health and recovery from inflammatory conditions. Learn how this natural enzyme may play a role in heart attack prevention and integrative health strategies.

David Stephen Klein, MD FACA FACPM
Mar 174 min read


Saphenous Neuralgia: The Frequently Missed Cause of Medial Knee and Leg Pain
Saphenous neuralgia is an under-recognized cause of medial knee and leg pain characterized by burning hypersensitivity without weakness. Often mistaken for arthritis or meniscal injury, it responds best to targeted nerve evaluation and ultrasound-guided treatment.

David Stephen Klein, MD FACA FACPM
Mar 95 min read


Migraine vs Sinus Headache
Migraines and sinus headaches are often confused because they can share facial pain, congestion, and watery eyes—but they are fundamentally different conditions that require different treatments. Migraines are a neurological disorder commonly associated with throbbing head pain, nausea, and sensitivity to light and sound, while true sinus headaches result from inflamed or infected sinus cavities and are typically accompanied by thick nasal discharge, fever, and pain that wors

David S. Klein, MD FACA FACPM
Jan 85 min read


Back Pain Due to Cluneal Nerve: Entrapment Cryptogenic Back Pain. When the Problem is NOT the Disc
Back and buttock pain that persists despite standard imaging and conservative therapy often leaves patients and clinicians searching for an underlying explanation. One frequently overlooked cause involves injury or entrapment of the cluneal nerves—three distinct sensory nerve groups that supply the skin over the lower back, sacrum, and buttocks. When compressed or inflamed, these nerves can generate pain syndromes that closely resemble lumbar radiculopathy, sacroiliac dysfunc

David S. Klein, MD FACA FACPM
Nov 28, 20256 min read


Hyaluronic Acid Supplementation: Improvement in Skin Health, Cardiac Health, Joint Health, and Vascular Health
Hyaluronic acid (HA) is a naturally occurring glycosaminoglycan found throughout the human body, most notably in the skin, joints, eyes, and blood vessels. It is a key player in hydration, lubrication, and tissue integrity. As our natural levels decline with age, supplementation has gained traction in dermatology, rheumatology, ophthalmology, and beyond. Below is an overview of the many health benefits of HA supplementation, along with practical guidance for use.

David S. Klein, MD FACA FACPM
Oct 15, 20253 min read


Understanding Plantar Fasciitis: Foot Pain Causes, Treatment, and Prevention
Plantar Fasciitis is a common cause of foot and heel pain. Worse in the morning, it can cause gait abnormalities, pain that is difficult to control, and impairment of activities of daily life.

David S. Klein, MD FACA FACPM
Sep 26, 20254 min read
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