Insulin resistance often develops years before diabetes, heart disease, or dementia are diagnosed. During this silent phase, metabolic dysfunction damages blood vessels, the brain, and cellular aging pathways. Understanding insulin resistance early allows for targeted intervention that can meaningfully reduce cardiovascular risk, cognitive decline, and accelerated biological aging.

Is It Dementia — or Is It Something Else? Cognitive decline is frequently assumed to represent dementia, yet a wide range of medical conditions can closely mimic neurodegenerative disease and are often treatable when identified early. Acute delirium, commonly triggered by infection, dehydration, metabolic abnormalities, or medication effects, is one of the most frequently missed causes of sudden confusion and cognitive change. Medications themselves, particularly anticholiner

Vitamin D is commonly thought of as a simple nutrient, but medically it functions as a steroid hormone with effects far beyond bone health. Unlike true vitamins, vitamin D is synthesized in the skin, activated through the liver and kidneys, and acts on receptors throughout the body to regulate gene expression. This hormonal role explains its influence on immune function, muscle strength, cardiovascular health, and brain function. Because deficiency is widespread and supplemen

St. John’s wort is often viewed as a safe, natural supplement, but it is one of the most dangerous herbal products when combined with prescription medications. By strongly inducing liver enzymes and drug transporters, it can lower blood levels of antidepressants, birth control pills, anticoagulants, and transplant medications—sometimes leading to serotonin syndrome, unintended pregnancy, stroke, or organ rejection.

THC may shorten sleep onset, but research shows it suppresses REM sleep and disrupts normal sleep architecture. Over time, this can impair memory, mood, and restorative sleep—especially with nightly use. Understanding the difference between sedation and healthy sleep is critical.

Natural compounds can enhance both mental and physical performance while also protecting long-term health. One intriguing candidate is Huperzine A—an extract from the Chinese club moss Huperzia serrata. Traditionally used in Eastern medicine for memory and clarity, this alkaloid has gained attention in modern research for its role in nitric oxide (NO) signaling, neuroprotection, erectile dysfunction, and vascular function.

Popular GLP-1 medications, like Ozempic and Zepbound may provide prevention of Alzheimer's Dementia on top of the weight reduction and diabetes control. Reduction of weight helps with Sleep Apnea, as well. Understand the need for medical monitoring if you are going to use these medications. This is a worthy read to give a comprehensive presentation as to the risks/benefits as well as the need for vigilance.

Statin medications may lower your cholesterol but the cost to you may be increased risk of dementia, worsening of your diabetes and increased weight gain.

Low dose lithium may be a useful tool in the treatment and prevention of memory loss and alzheimer's disease. Well below the dosages used to treat psychiatric disorders, low dose lithium may provide symptomatic relief and may forestall or prevent the development of age related memory loss and dementia.

The Glycocalyx is the lining layer within the blood vessels and the gut. It is easily damaged and it becomes the epicenter of pathology that shortens life span, decreases health and it is easily maintained to prevent heart disease and stroke.