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THC, REM Sleep, and the Quiet Disruption of Sleep Architecture
THC may shorten sleep onset, but research shows it suppresses REM sleep and disrupts normal sleep architecture. Over time, this can impair memory, mood, and restorative sleep—especially with nightly use. Understanding the difference between sedation and healthy sleep is critical.

David S. Klein, MD FACA FACPM
5 days ago5 min read


Huperzine A: Nitric Oxide for Erectile Dysfunction, Dementia. Benefits and Side Effects
Natural compounds can enhance both mental and physical performance while also protecting long-term health. One intriguing candidate is Huperzine A—an extract from the Chinese club moss Huperzia serrata. Traditionally used in Eastern medicine for memory and clarity, this alkaloid has gained attention in modern research for its role in nitric oxide (NO) signaling, neuroprotection, erectile dysfunction, and vascular function.

David S. Klein, MD FACA FACPM
Dec 26, 20256 min read


GLP-1 Medications and Dementia Prevention. Weight Loss, Diabetes Risk Reduction and Alzheimer's Prevention, as a Bonus!
Popular GLP-1 medications, like Ozempic and Zepbound may provide prevention of Alzheimer's Dementia on top of the weight reduction and diabetes control.
Reduction of weight helps with Sleep Apnea, as well. Understand the need for medical monitoring if you are going to use these medications.
This is a worthy read to give a comprehensive presentation as to the risks/benefits as well as the need for vigilance.

David S. Klein, MD FACA FACPM
Sep 23, 202512 min read


Your Statin Medication May be Increasing your Risk of Alzheimer's Dementia, Raising your Risk of Diabetes and may be making it harder to lose weight. Learn more....
Statin medications may lower your cholesterol but the cost to you may be increased risk of dementia, worsening of your diabetes and increased weight gain.

David S. Klein, MD FACA FACPM
Sep 19, 20258 min read


The Benefits of Lithium: An Emerging Role in Memory Loss & Alzheimer’s Prevention and Treatment
Low dose lithium may be a useful tool in the treatment and prevention of memory loss and alzheimer's disease. Well below the dosages used to treat psychiatric disorders, low dose lithium may provide symptomatic relief and may forestall or prevent the development of age related memory loss and dementia.

David S. Klein, MD FACA FACPM
Aug 19, 20255 min read


The Glycocalyx: The Largely Unrecognized Center of Cardiac, Kidney and Gut Illness. This may be the most important piece of medical trivia that you need to know.
The Glycocalyx is the lining layer within the blood vessels and the gut. It is easily damaged and it becomes the epicenter of pathology that shortens life span, decreases health and it is easily maintained to prevent heart disease and stroke.

David S. Klein, MD FACA FACPM
Apr 11, 20257 min read


Exploring the Diverse World of Magnesium Chelates and Products: Pros and Cons Unveiled. Choose Intelligently
Magnesium deficiency plagues 30% of the US population. We discuss the relative advantages and subtle differences between different products

David S. Klein, MD FACA FACPM
Mar 22, 202510 min read


Outside the Box Thinking on What Might Contribute to Alzheimer's Dementia: The Glycocalyx. The Structure and Function of the Glycocalyx and Its Connection With Blood-Brain Barrier.
An interesting article that may enlighten us as to what might be going wrong leading to dementia.

David S. Klein, MD FACA FACPM
Mar 5, 20254 min read


The Many Advantages of adding Hyaluronic Acid: A Comprehensive Discussion of Cardiac and Gastrointestinal Benefits, chronic disease treatment and prevention.
Adding high molecular weight, liquid Hyaluronic Acid to your daily routine provides tremendous health benefits at a remarkable value.

David S. Klein, MD FACA FACPM
Feb 28, 20255 min read


Why Are Elevated Uric Acid Levels Linked to an Increased Risk of Heart Attack?
Uric acid is an independent factor that is important in the development of vascular heart disease. Get your levels below 5.4 mg/dl

David S. Klein, MD FACA FACPM
Dec 6, 20245 min read
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