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Visceral Adiposity: Why Belly Fat Is A Metabolic And Longevity Risk
Visceral fat is not merely stored energy—it is a biologically active tissue that drives insulin resistance, cardiovascular disease, cognitive decline, and accelerated aging. Many individuals with normal weight harbor excess visceral fat. Identifying and reducing it early can dramatically improve metabolic health and long-term healthspan.

David S. Klein, MD FACA FACPM
17 hours ago3 min read


Saphenous Neuralgia: The Frequently Missed Cause of Medial Knee and Leg Pain
Saphenous neuralgia is an under-recognized cause of medial knee and leg pain characterized by burning hypersensitivity without weakness. Often mistaken for arthritis or meniscal injury, it responds best to targeted nerve evaluation and ultrasound-guided treatment.

David Stephen Klein, MD FACA FACPM
1 day ago5 min read


Hyperuricemia and Eye Disease: The Ocular Consequences of Elevated Uric Acid
Elevated uric acid is increasingly linked to glaucoma, retinal vascular disease, macular degeneration, and ocular inflammation. Through endothelial dysfunction and oxidative stress, hyperuricemia may impair ocular microcirculation. Evaluating uric acid levels may be an overlooked step in protecting long-term visual and vascular health.

David Stephen Klein, MD FACA FACPM
4 days ago3 min read


Graves’ Disease vs. Hashimoto’s Thyroiditis
Graves’ disease and Hashimoto’s thyroiditis are autoimmune thyroid disorders with opposite effects—one overstimulates the gland, the other progressively destroys it. Though they share immune origins, their symptoms, labs, and long-term risks differ significantly. Accurate diagnosis is essential to prevent cardiovascular, skeletal, and neurocognitive complications and to guide precise, individualized treatment.

David Stephen Klein, MD FACA FACPM
6 days ago4 min read


Vitamin D and Thyroid Function
Vitamin D plays a critical role in thyroid health by regulating immune tolerance, gene expression, and thyroid hormone sensitivity. Low vitamin D levels are strongly associated with autoimmune thyroid diseases such as Hashimoto’s thyroiditis and Graves’ disease, as well as persistent hypothyroid symptoms despite “normal” lab values. Optimizing vitamin D supports immune balance, improves thyroid hormone signaling, and may reduce autoimmune activity.

David Stephen Klein, MD FACA FACPM
Mar 34 min read


Seasonal Affective Disorder
Seasonal affective disorder is not simply “winter blues,” but a biologically driven condition caused by reduced light exposure and circadian disruption. Shortened daylight alters melatonin, serotonin, and cortisol signaling, leading to fatigue, low mood, sleep disturbance, and cognitive slowing. When recognized early and treated with targeted light therapy, vitamin D repletion, and circadian-based interventions, seasonal affective disorder is highly manageable and often fully

David Stephen Klein, MD FACA FACPM
Feb 284 min read


Overfunctioning: When Competence Becomes a Coping Strategy
Overfunctioning is not a psychiatric diagnosis but a behavioral pattern rooted in adaptation. It can create stability, achievement, and leadership—yet when rigid or chronic, it fuels burnout, resentment, and physiologic stress. This article explores how overfunctioning becomes harmful, how it affects relationships and stress hormones, and how to restore flexibility without sacrificing competence.

David Stephen Klein, MD FACA FACPM
Feb 285 min read


Alpha-Gal Allergy: The Lone Star Tick and the Red Meat Reaction
Alpha-gal syndrome is a delayed allergic reaction to red meat triggered by the Lone Star tick. Unlike typical food allergies, symptoms may occur 3–8 hours after eating beef, pork, or lamb. Learn how tick exposure alters immune signaling, why reactions are delayed, how to diagnose alpha-gal IgE, and what steps help prevent serious allergic complications.

David Stephen Klein, MD FACA FACPM
Feb 253 min read


Atherogenic Dyslipidemia: Why Triglycerides and HDL Matter More Than LDL Alone
Atherogenic dyslipidemia—marked by high triglycerides, low HDL, and small dense LDL—often hides behind normal LDL cholesterol. This insulin-resistant lipid pattern predicts cardiovascular disease earlier and more accurately than LDL alone.

David S. Klein, MD FACA FACPM
Feb 243 min read


Baastrup’s Disease: The Overlooked Cause of Midline Low Back Pain
Baastrup’s disease—also called kissing spine syndrome—is a degenerative condition in which adjacent lumbar spinous processes contact one another, producing focal midline back pain. Often mistaken for disc disease, it typically worsens with extension and improves with flexion. Accurate diagnosis allows targeted treatment and may prevent unnecessary procedures.

David Stephen Klein, MD FACA FACPM
Feb 224 min read
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