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The Genetic Hand You're Dealt: Life Is a Game of Five-Card Poker. Genetics and Epigenetics
Your genes are like the cards you're dealt in a poker game. Some people inherit a greater risk of diabetes, heart disease, Alzheimer's, or cancer, but genetic predisposition does not guarantee disease. Diet, sleep, stress, trauma, environmental exposures, and epigenetic regulation can influence how inherited risks unfold. Discover how everyday choices may change the odds of chronic disease and premature aging. A genetic predisposition is a reason for vigilance, not a declarat

David Stephen Klein, MD FACA FACPM
1 day ago9 min read


Can Ferrous Sulfate Raise Ferritin? When Iron Supplements Help—or Hurt. Low Ferritin?
Can ferrous sulfate raise ferritin levels? Learn how oral iron supplements replenish iron stores, how hepcidin regulates absorption, and why low ferritin may contribute to fatigue and hair loss. Discover when iron supplementation is beneficial, why increasing ferritin does not guarantee hair regrowth, and the potential risks of unnecessary iron therapy. Understanding the cause of low ferritin is essential to choosing safe, effective treatment.

David Stephen Klein, MD FACA FACPM
Oct 219 min read


Your Ferritin May Be Low or “In Range”—But Is It Too Low for Healthy Hair?
Your ferritin may be marked “normal,” but does that mean your iron stores are adequate when you are losing hair? Iron deficiency can develop before anemia, and lower ferritin has been associated with telogen effluvium. But there is no proven universal ferritin target for hair growth—and low ferritin should not automatically mean taking iron. Learn why ferritin is a diagnostic clue, what can cause depleted iron stores, and why unexplained hair loss deserves a broader evaluatio

David Stephen Klein, MD FACA FACPM
Oct 110 min read


Your Fasting Glucose Is Normal—but Is Your Insulin?
A normal fasting glucose does not always mean normal metabolic health. During early insulin resistance, the pancreas may compensate by producing more insulin, keeping glucose deceptively normal. Measuring fasting insulin alongside glucose may reveal this hidden metabolic stress earlier. Learn why fasting insulin, HOMA-IR, A1c, triglycerides, waist circumference, and other markers can provide a more complete picture of insulin resistance and metabolic health.

David Stephen Klein, MD FACA FACPM
Sep 298 min read


Dandelion Extract for Urinary Tract Infections: An Adjunct to D-Mannose and Antibiotic Therapy
Dandelion extract may offer supportive benefits for urinary tract infections by promoting urine flow and helping the urinary tract naturally flush itself. Its role is adjunctive—not a replacement for appropriate treatment. When used alongside D-mannose, adequate hydration, and antibiotics when clinically indicated, dandelion may become part of a broader strategy for urinary health, particularly in patients with recurrent or persistent urinary symptoms.

David Stephen Klein, MD FACA FACPM
Sep 249 min read


Extreme Heat, Heavy Sweating, and Salt Loss: When Water Is Not Enough
Extreme heat and prolonged sweating cause the body to lose more than water. Sodium losses during hiking, exercise, gardening, landscaping, and outdoor work can become substantial. Learn how much salt may be lost through sweat, when water alone is sufficient, when electrolyte replacement becomes important, why drinking too much plain water can also be dangerous, and which symptoms mean it is time to stop self-treatment and seek medical care.

David Stephen Klein, MD FACA FACPM
Aug 199 min read


Uric Acid and Hypertension: Is Your Uric Acid Helping Drive Your Blood Pressure?
Uric acid is best known for gout, but elevated levels are also associated with hypertension, kidney dysfunction, and cardiovascular risk. Research suggests that uric acid may influence blood pressure through oxidative stress, reduced nitric oxide, renin-angiotensin activation, renal vasoconstriction, and altered sodium handling. Learn how uric acid, kidney function, and hypertension may form a self-reinforcing cycle—and why lowering uric acid is not always the same as lowerin

David Stephen Klein, MD FACA FACPM
Aug 179 min read


Pulse Pressure, Aging, and Stroke Risk: Why the “Ideal” Number Changes With Age
Pulse pressure is the difference between systolic and diastolic blood pressure. For example, 120/80 mmHg produces a pulse pressure of 40 mmHg. Pulse pressure often widens with age as large arteries become stiffer. In older adults, a persistently wide pulse pressure may indicate increased arterial stiffness and cardiovascular risk, including stroke risk. It should be interpreted together with age, systolic and diastolic pressures, medical conditions, and overall cardiovascular

David Stephen Klein, MD FACA FACPM
Aug 149 min read


The Longevity Pulse: What Your Resting Heart Rate Says About Your Health
Your resting heart rate is more than just a number—it is a powerful biomarker of cardiovascular fitness, autonomic nervous system balance, metabolic health, and healthy aging. Learn why "normal" may not always mean "optimal," what research reveals about heart rate and longevity, and how exercise, sleep, nutrition, stress management, and overall health influence your pulse. Discover practical strategies to improve cardiovascular efficiency and support a longer, healthier life.

David Stephen Klein, MD FACA FACPM
Aug 1010 min read


Low-Dose Lithium for Mild to Moderate Depression: Can a Time-Tested Mineral Improve Mood, Protect the Brain, and Promote Healthy Aging?
Could a medication long used for bipolar disorder also help support mood, protect the brain, and promote healthy aging at much lower doses? Emerging research suggests low-dose lithium may enhance neuroplasticity, reduce neuroinflammation, improve mitochondrial function, and influence pathways involved in depression and cognitive decline. Learn the current science, safety considerations, and how a systems-based evaluation may improve outcomes.

David Stephen Klein, MD FACA FACPM
Jul 2812 min read
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