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Glymphatic Drainage, Alzheimer's Disease, and How to Protect Your Brain. part 2
Does your brain actually shrink while you sleep? Scientists have discovered that spaces between brain cells may expand during sleep, potentially allowing cerebrospinal fluid to circulate more freely and transport metabolic waste. This process, called glymphatic drainage, may influence brain health, memory, and the accumulation of proteins associated with Alzheimer's disease. Discover what the research reveals about the brain's remarkable nighttime housekeeping system.

David Stephen Klein, MD FACA FACPM
7 hours ago11 min read


Does Your Brain Actually Shrink During Sleep? Understanding Glymphatic Drainage. Alzheimers Prevention?
Glymphatic Drainage, Glymphatic System, Brain Health, Brain Aging, Cognitive Health, Alzheimer's Disease, Dementia Prevention, Neurodegenerative Disease, Sleep Health, Deep Sleep, Restorative Sleep, Sleep Quality, Sleep Disorders, Memory and Cognition, Healthy Aging, Longevity Medicine, Functional Medicine, Integrative Medicine, Preventive Medicine, Metabolic Health, Brain Waste Clearance, Cerebrospinal Fluid, Brain Shrinkage During Sleep, Amyloid Beta Clearance, Tau Protein,

David Stephen Klein, MD FACA FACPM
4 days ago9 min read


Why Do My Eyes Twitch? Common Causes, Deficiencies, and Warning Signs: part 1
Why do my eyes twitch? Eyelid twitching, medically known as myokymia, is usually harmless but can be frustrating. Common triggers include stress, poor sleep, caffeine, dry eyes, and ocular irritation. Although magnesium deficiency is often suspected, it is rarely the proven cause. Learn what causes involuntary eyelid spasms, how to relieve them, and which warning signs may indicate an underlying neurological condition requiring medical evaluation.

David Stephen Klein, MD FACA FACPM
Oct 158 min read


C15:0 (Pentadecanoic Acid): Could This Be the First Newly Recognized Essential Fatty Acid in Nearly 100 Years?
Could C15:0 (pentadecanoic acid) become the first newly recognized essential fatty acid in nearly a century? Emerging research suggests this naturally occurring odd-chain saturated fatty acid may support healthy cell membranes, mitochondrial function, metabolic health, and healthy aging. Learn what current science tells us about food sources, supplements, recommended intake, and why researchers are paying close attention to this unique nutrient.

David Stephen Klein, MD FACA FACPM
Aug 77 min read


Pepto-Bismol®: An Under-appreciated Treatment for Dyspepsia, Traveler's Diarrhea, and Foodborne Illness Prevention
Discover the evidence-based uses of Pepto-Bismol® for functional dyspepsia, traveler's diarrhea, foodborne illness, and Helicobacter pylori. Learn when it works, how to use it safely, and why this century-old medication remains an important part of modern digestive care.

David Stephen Klein, MD FACA FACPM
Aug 65 min read


Pre-Diabetes: Insulin Resistance, Is It a Real Condition — Or a Warning Sign We Ignore at Our Own Risk?
Many people are told they have pre-diabetes and assume it simply means they may someday develop diabetes.
The truth is far more concerning.
Long before someone officially develops Type 2 diabetes, elevated insulin levels and subtle abnormalities in blood sugar regulation may already be damaging blood vessels, nerves, kidneys, and even the brain.
Prediabetes is not almost disease.
It is often the earliest measurable sign that metabolic dysfunction has already begun.
The g

David Stephen Klein, MD FACA FACPM
Jul 36 min read


How Room Humidity Affects Sleep Quality: An Overlooked Variable in Restorative Sleep
Most people focus on sleep duration, mattress quality, or circadian rhythm when trying to improve sleep. Few realize that bedroom humidity can profoundly influence airway comfort, thermoregulation, snoring, sleep fragmentation, and even overnight hormone balance. Maintaining proper humidity may be one of the simplest and least appreciated interventions for improving restorative sleep.

David S. Klein, MD FACA FACPM
Jun 235 min read


Vyepti® for Migraine Prevention: IV Treatment, Benefits, Risks, and Insurance Steps
Vyepti® (eptinezumab) is a quarterly intravenous treatment designed to prevent migraines before they begin. Unlike daily medications or monthly injections, Vyepti is administered only four times per year and targets CGRP, a key migraine signaling molecule. Learn how this innovative therapy works, who may qualify, what side effects to consider, and the insurance steps often required before treatment can begin. This guide reviews the benefits, risks, and practical consideration

David Stephen Klein, MD FACA FACPM
Jun 125 min read


GLP-1 Medications and Dementia Prevention. Weight Loss, Diabetes Risk Reduction and Alzheimer's Prevention, as a Bonus!
Popular GLP-1 medications, like Ozempic and Zepbound may provide prevention of Alzheimer's Dementia on top of the weight reduction and diabetes control.
Reduction of weight helps with Sleep Apnea, as well. Understand the need for medical monitoring if you are going to use these medications.
This is a worthy read to give a comprehensive presentation as to the risks/benefits as well as the need for vigilance.

David S. Klein, MD FACA FACPM
Sep 23, 202512 min read
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