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Vitamin D in Midlife May Reduce Future Tau Protein Burden: Implications for Dementia Prevention
A major new study published in Neurology demonstrated that individuals with higher circulating vitamin D levels during midlife showed significantly lower tau protein accumulation in the brain nearly two decades later. Tau protein accumulation is one of the central pathological hallmarks of Alzheimer’s disease and other neurodegenerative disorders. These findings suggest vitamin D optimization during midlife may represent an overlooked but potentially powerful intervention for

David Stephen Klein, MD FACA FACPM
Jun 156 min read


Insulin Resistance: The Hidden Precursor to Cardiovascular Disease, Dementia, and Accelerated Aging
Insulin resistance develops silently years before diabetes, accelerating heart disease, cognitive decline, and aging. Early detection with proper lab testing allows effective, targeted intervention to reverse risk and restore metabolic health.

David Stephen Klein, MD FACA FACPM
May 123 min read


Visceral Adiposity: Why Belly Fat Is A Metabolic And Longevity Risk
Visceral fat is not merely stored energy—it is a biologically active tissue that drives insulin resistance, cardiovascular disease, cognitive decline, and accelerated aging. Many individuals with normal weight harbor excess visceral fat. Identifying and reducing it early can dramatically improve metabolic health and long-term healthspan.

David S. Klein, MD FACA FACPM
Mar 103 min read
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