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Can a Simple CBC Predict Future Dementia Risk?
The Monocyte-to-Lymphocyte Ratio and Its Emerging Role in Cognitive Decline. One of the cheapest test that is currently available. Can a Simple CBC Predict Future Dementia Risk? Understanding how the Monocyte-to-Lymphocyte Ratio (MLR) may reveal early inflammatory changes associated with Alzheimer’s disease, vascular dementia, and accelerated cognitive aging. Quick Look Could a routine complete blood count reveal early warning signs of future dementia? A growing body of evide

David Stephen Klein, MD FACA FACPM
5 days ago5 min read


Vitamin D in Midlife May Reduce Future Tau Protein Burden: Implications for Dementia Prevention
A major new study published in Neurology demonstrated that individuals with higher circulating vitamin D levels during midlife showed significantly lower tau protein accumulation in the brain nearly two decades later. Tau protein accumulation is one of the central pathological hallmarks of Alzheimer’s disease and other neurodegenerative disorders. These findings suggest vitamin D optimization during midlife may represent an overlooked but potentially powerful intervention for

David Stephen Klein, MD FACA FACPM
Jun 156 min read


What is a Vitamin?
What is a vitamin? A physician explains vitamin definitions, deficiencies, supplementation, and why vitamin D is actually a hormone.

David S. Klein, MD FACA FACPM
Jan 134 min read


The Benefits of Lithium: An Emerging Role in Memory Loss & Alzheimer’s Prevention and Treatment
Low dose lithium may be a useful tool in the treatment and prevention of memory loss and alzheimer's disease. Well below the dosages used to treat psychiatric disorders, low dose lithium may provide symptomatic relief and may forestall or prevent the development of age related memory loss and dementia.

David S. Klein, MD FACA FACPM
Aug 19, 20255 min read
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