Lactoferrin-rich colostrum occupies a unique niche at the intersection of mucosal immunity, systemic inflammatory control, and sleep regulation. By combining the broad matrix of colostrum with the targeted antiviral, antibacterial, and immunomodulatory activity of lactoferrin, these preparations can reduce the burden of upper respiratory infections, support resilient immune function, and modestly improve sleep quality in selected populations. As with any therapeutic nutrient,