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The Long Shadow of Influenza: Can the Flu Affect the Brain Decades Later? Trigger Dementia?
Influenza usually lasts days or weeks—but could its effects on the brain last much longer? From von Economo's mysterious encephalitis lethargica to modern research linking severe infections with neuroinflammation and later dementia, scientists are reconsidering the long-term neurologic consequences of infection. The evidence does not prove that influenza causes dementia, but it raises an important question: can infection alter the trajectory of an aging brain?

David Stephen Klein, MD FACA FACPM
3 days ago13 min read


Vyepti® for Migraine Prevention: IV Treatment, Benefits, Risks, and Insurance Steps
Vyepti® (eptinezumab) is a quarterly intravenous treatment designed to prevent migraines before they begin. Unlike daily medications or monthly injections, Vyepti is administered only four times per year and targets CGRP, a key migraine signaling molecule. Learn how this innovative therapy works, who may qualify, what side effects to consider, and the insurance steps often required before treatment can begin. This guide reviews the benefits, risks, and practical consideration

David Stephen Klein, MD FACA FACPM
Jun 125 min read


GLP-1 Medications and Dementia Prevention. Weight Loss, Diabetes Risk Reduction and Alzheimer's Prevention, as a Bonus!
Popular GLP-1 medications, like Ozempic and Zepbound may provide prevention of Alzheimer's Dementia on top of the weight reduction and diabetes control.
Reduction of weight helps with Sleep Apnea, as well. Understand the need for medical monitoring if you are going to use these medications.
This is a worthy read to give a comprehensive presentation as to the risks/benefits as well as the need for vigilance.

David S. Klein, MD FACA FACPM
Sep 23, 202512 min read


Outside the Box Thinking on What Might Contribute to Alzheimer's Dementia: The Glycocalyx. The Structure and Function of the Glycocalyx and Its Connection With Blood-Brain Barrier.
An interesting article that may enlighten us as to what might be going wrong leading to dementia.

David S. Klein, MD FACA FACPM
Mar 5, 20254 min read
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