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Dandelion Extract for Urinary Tract Infections: An Adjunct to D-Mannose and Antibiotic Therapy
Dandelion extract may offer supportive benefits for urinary tract infections by promoting urine flow and helping the urinary tract naturally flush itself. Its role is adjunctive—not a replacement for appropriate treatment. When used alongside D-mannose, adequate hydration, and antibiotics when clinically indicated, dandelion may become part of a broader strategy for urinary health, particularly in patients with recurrent or persistent urinary symptoms.

David Stephen Klein, MD FACA FACPM
Sep 249 min read


Could You Be Running Low on Glycine?
Glycine is considered a nonessential amino acid because the body can make it—but can it always make enough? Emerging evidence suggests that aging, insulin resistance, oxidative stress, and increased connective-tissue demands may create a mismatch between glycine supply and metabolic need. Learn about possible signs of glycine insufficiency, plasma amino-acid testing, glycine-rich foods, sleep dosing, collagen, glutathione, and GlyNAC.

David Stephen Klein, MD FACA FACPM
Sep 1411 min read


Environmental Heat, Alcohol, and Hyponatremia. Deadly in Summer
Hot weather can create more than dehydration. Sweating causes water and sodium loss, while heat-related vasodilation can lower blood pressure. Add alcohol, medications, poor food intake, or excessive plain water and the result may be orthostatic dizziness, hyponatremia, instability, and falls. Learn why older adults are especially vulnerable, which medications increase risk, when electrolyte replacement may matter, and which symptoms require urgent medical evaluation.

David Stephen Klein, MD FACA FACPM
Sep 1014 min read


Extreme Heat, Heavy Sweating, and Salt Loss: When Water Is Not Enough
Extreme heat and prolonged sweating cause the body to lose more than water. Sodium losses during hiking, exercise, gardening, landscaping, and outdoor work can become substantial. Learn how much salt may be lost through sweat, when water alone is sufficient, when electrolyte replacement becomes important, why drinking too much plain water can also be dangerous, and which symptoms mean it is time to stop self-treatment and seek medical care.

David Stephen Klein, MD FACA FACPM
Aug 199 min read


Uric Acid and Hypertension: Is Your Uric Acid Helping Drive Your Blood Pressure?
Uric acid is best known for gout, but elevated levels are also associated with hypertension, kidney dysfunction, and cardiovascular risk. Research suggests that uric acid may influence blood pressure through oxidative stress, reduced nitric oxide, renin-angiotensin activation, renal vasoconstriction, and altered sodium handling. Learn how uric acid, kidney function, and hypertension may form a self-reinforcing cycle—and why lowering uric acid is not always the same as lowerin

David Stephen Klein, MD FACA FACPM
Aug 179 min read


Pulse Pressure, Aging, and Stroke Risk: Why the “Ideal” Number Changes With Age
Pulse pressure is the difference between systolic and diastolic blood pressure. For example, 120/80 mmHg produces a pulse pressure of 40 mmHg. Pulse pressure often widens with age as large arteries become stiffer. In older adults, a persistently wide pulse pressure may indicate increased arterial stiffness and cardiovascular risk, including stroke risk. It should be interpreted together with age, systolic and diastolic pressures, medical conditions, and overall cardiovascular

David Stephen Klein, MD FACA FACPM
Aug 149 min read


The Longevity Pulse: What Your Resting Heart Rate Says About Your Health
Your resting heart rate is more than just a number—it is a powerful biomarker of cardiovascular fitness, autonomic nervous system balance, metabolic health, and healthy aging. Learn why "normal" may not always mean "optimal," what research reveals about heart rate and longevity, and how exercise, sleep, nutrition, stress management, and overall health influence your pulse. Discover practical strategies to improve cardiovascular efficiency and support a longer, healthier life.

David Stephen Klein, MD FACA FACPM
Aug 1010 min read


Low-Dose Lithium for Mild to Moderate Depression: Can a Time-Tested Mineral Improve Mood, Protect the Brain, and Promote Healthy Aging?
Could a medication long used for bipolar disorder also help support mood, protect the brain, and promote healthy aging at much lower doses? Emerging research suggests low-dose lithium may enhance neuroplasticity, reduce neuroinflammation, improve mitochondrial function, and influence pathways involved in depression and cognitive decline. Learn the current science, safety considerations, and how a systems-based evaluation may improve outcomes.

David Stephen Klein, MD FACA FACPM
Jul 2812 min read


Quercetin for Diabetes and Insulin Resistance: Could Nature's SGLT-2 Inhibitor Support Better Metabolic Health?
Quercetin is a plant compound found in onions, apples, berries, and capers. Emerging research suggests that certain forms may influence glucose absorption and some of the transport pathways associated with SGLT activity. Could this help support diabetes, insulin resistance, weight management, and metabolic health? Learn what is established, what remains theoretical, and why quercetin should complement—not replace—appropriate medical treatment.

David Stephen Klein, MD FACA FACPM
Jul 2413 min read


Adrenal Dysfunction and Adrenal Fatigue: Vital to Life, Yet Often Overlooked in Modern Medicine
The adrenal glands are among the body’s most vital yet overlooked organs, controlling stress adaptation, inflammation, blood pressure, metabolism, immune balance, and energy production. While severe adrenal failure such as Addison’s Disease is recognized in medicine, milder adrenal dysfunction often goes undiagnosed for years. Chronic stress, poor sleep, illness, medications, and nutritional deficiencies can impair adrenal function long before traditional testing reveals dise

David Stephen Klein, MD FACA FACPM
Jul 215 min read
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