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Huperzine A: Nitric Oxide for Erectile Dysfunction, Dementia. Benefits and Side Effects
Natural compounds can enhance both mental and physical performance while also protecting long-term health. One intriguing candidate is Huperzine A—an extract from the Chinese club moss Huperzia serrata. Traditionally used in Eastern medicine for memory and clarity, this alkaloid has gained attention in modern research for its role in nitric oxide (NO) signaling, neuroprotection, erectile dysfunction, and vascular function.

David S. Klein, MD FACA FACPM
Dec 26, 20256 min read


Hyaluronic Acid Supplementation: Improvement in Skin Health, Cardiac Health, Joint Health, and Vascular Health
Hyaluronic acid (HA) is a naturally occurring glycosaminoglycan found throughout the human body, most notably in the skin, joints, eyes, and blood vessels. It is a key player in hydration, lubrication, and tissue integrity. As our natural levels decline with age, supplementation has gained traction in dermatology, rheumatology, ophthalmology, and beyond. Below is an overview of the many health benefits of HA supplementation, along with practical guidance for use.

David S. Klein, MD FACA FACPM
Oct 15, 20253 min read


Outside the Box Thinking on What Might Contribute to Alzheimer's Dementia: The Glycocalyx. The Structure and Function of the Glycocalyx and Its Connection With Blood-Brain Barrier.
An interesting article that may enlighten us as to what might be going wrong leading to dementia.

David S. Klein, MD FACA FACPM
Mar 5, 20254 min read
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