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THC, REM Sleep, and the Quiet Disruption of Sleep Architecture
THC may shorten sleep onset, but research shows it suppresses REM sleep and disrupts normal sleep architecture. Over time, this can impair memory, mood, and restorative sleep—especially with nightly use. Understanding the difference between sedation and healthy sleep is critical.

David S. Klein, MD FACA FACPM
5 days ago5 min read


Huperzine A: Nitric Oxide for Erectile Dysfunction, Dementia. Benefits and Side Effects
Natural compounds can enhance both mental and physical performance while also protecting long-term health. One intriguing candidate is Huperzine A—an extract from the Chinese club moss Huperzia serrata. Traditionally used in Eastern medicine for memory and clarity, this alkaloid has gained attention in modern research for its role in nitric oxide (NO) signaling, neuroprotection, erectile dysfunction, and vascular function.

David S. Klein, MD FACA FACPM
Dec 26, 20256 min read


THE HIDDEN CAUSES OF PERSISTENT FATIGUE: A PHYSICIAN’S GUIDE TO OVERLOOKED METABOLIC AND ENDOCRINE DISORDERS
Chronic fatigue often signals hidden metabolic or endocrine disorders. Learn the overlooked causes—from thyroid and iron issues to insulin resistance and mitochondria.

David S. Klein, MD FACA FACPM
Dec 24, 20254 min read
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